2-(2-氨基苯基)吲哚合成路线 （共 32 条）
反应条件
Au/Carbon G-60 catalyst in toluene T=90°C; 24 h; Inert atmosphereSchlenk technique;
参考文献
Perea-Buceta, Jesus E.; Wirtanen, Tom; Laukkanen, Otto-Ville; Maekelae, Mikko K.; Nieger, Martin; Melchionna, Michele; Huittinen, Nina; Lopez-Sanchez, Jose A.; Helaja, Juho
Angewandte Chemie - International Edition, 2013 , vol. 52, # 45 p. 11835 - 11839
Angew. Chem., 2013 , vol. 125, # 45 p. 12051 - 12055,5
反应条件
methanesulfonic acid; phosphorus pentoxide T=80°C; 0.5 h;
参考文献
Billimoria, Adil D.; Cava, Michael P.
Journal of Organic Chemistry, 1994 , vol. 59, # 22 p. 6777 - 6782
反应条件
hydrogenchloride; iron in ethanol; water
参考文献
Kraus, George A.; Guo, Haitao; Kumar, Ganesh; Pollock Iii, Gerald; Carruthers, Heather; Chaudhary, Divya; Beasley, Jonathan
Synthesis, 2010 , # 8 art. no. Z27809SS, p. 1386 - 1393
反应条件
1: AcOH / ethanol / 6 h / Heating 2: methanesulfonic acid; P2O5 / 0.5 h / 80 °C View Scheme
参考文献
Tetrahedron, , vol. 59, # 7 p. 1033 - 1048
反应条件
selenium; water; caesium carbonate in isobutyramide T=100°C; P=22801.5 Torr; 5 h; Autoclave;
参考文献
Heteroatom Chemistry, , vol. 22, # 3-4 p. 571 - 575
反应条件
selenium; potassium carbonate in isobutyramide T=100°C; P=22801.5 Torr; 5 h; Autoclave;
参考文献
Heteroatom Chemistry, , vol. 22, # 3-4 p. 571 - 575
反应条件
methanesulfonic acid; phosphorous pentoxide in ethanol; acetic acid T=85°C; Fischer indole synthesis;
参考文献
Journal of the Brazilian Chemical Society, , vol. 21, # 5 p. 897 - 904
反应条件
1: 81 percent / CuI; Et3N; PdCl2(PPh3)2 / tetrahydrofuran / 3 h / 20 °C 2: 82 percent / KH / 1-methyl-pyrrolidin-2-one / 3 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 59, # 9 p. 1571 - 1587
反应条件
1: 92 percent / TBAF / tetrahydrofuran / 0.5 h / 20 °C 2: 81 percent / CuI; Et3N; PdCl2(PPh3)2 / tetrahydrofuran / 3 h / 20 °C 3: 82 percent / KH / 1-methyl-pyrrolidin-2-one / 3 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 59, # 9 p. 1571 - 1587
反应条件
methanesulfonic acid; phosphorous pentoxide T=85°C; Fischer indole cyclization;
参考文献
Archiv der Pharmazie, , vol. 342, # 9 p. 533 - 540
