2-(2-氨基苯基)吲哚合成路线 （共 32 条）
反应条件
1: 34 percent / aq. HCl / methanol / 25 h / 20 °C 2: 70 percent / AcOH / 1 h / Heating View Scheme
参考文献
Molina, Pedro; Alajarin, Mateo; Vidal, Angel
Tetrahedron, 1990 , vol. 46, # 3 p. 1063 - 1078
反应条件
acetic acid 2 h; Heating;
参考文献
Bergman, Jan; Engqvist, Robert; Stalhandske, Claes; Wallberg, Hans
Tetrahedron, 2003 , vol. 59, # 7 p. 1033 - 1048
参考文献
Journal of the Chemical Society, , p. 1319,1329
反应条件
trifluoroacetic acid in acetonitrile
T=80°C; Pictet-Spengler cyclisation; 2 h;
参考文献
Agarwal, Piyush K.; Sawant, Devesh; Sharma, Sunil; Kundu, Bijoy
European Journal of Organic Chemistry, 2009 , # 2 p. 292 - 303
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydroxide in tetrahydrofuran; water
1 h;
参考文献
Dalton, Lesley; Humphrey, Godfred L.; Cooper, Melanie M.; Joule, John A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 10 p. 2417 - 2422
反应条件
potassium; tert-butyl alcohol
参考文献
Kiang et al.
Journal of the Chemical Society, 1956 , p. 1319,1329
反应条件
1: in tetrahydrofuran
T=50°C; 2 h;
2: With methanol; lithium hydroxide; water in tetrahydrofuran
T=50°C;
参考文献
Bristol-Myers Squibb Company
Patent: US2006/293336 A1, 2006 ;
Location in patent: Page/Page column 39-40 ;
US 20060293336 A1
反应条件
hydrogenchloride; chloroform
T=50°C;
参考文献
Kiang et al.
Journal of the Chemical Society, 1956 , p. 1319,1329
反应条件
hydrogenchloride; chloroform
T=15°C;
参考文献
Kiang et al.
Journal of the Chemical Society, 1956 , p. 1319,1329
