4-氯-6-(甲氧基甲基)-2-苯基嘧啶合成路线 （共 11 条）
反应条件
1: NaOMe / methanol; ethanol / 21 h / Heating 2: 29.0 g / POCl3 / 3 h / Heating View Scheme
参考文献
Chemistry - A European Journal, , vol. 6, # 22 p. 4124 - 4131
反应条件
1: NaOMe / methanol; ethanol / 21 h / Heating 2: 29.0 g / POCl3 / 3 h / Heating View Scheme
参考文献
Chemistry - A European Journal, , vol. 6, # 22 p. 4124 - 4131
反应条件
trichlorophosphate 3 h; Heating;
参考文献
Gardinier, Kevin M.; Khoury, Richard G.; Lehn, Jean-Marie
Chemistry - A European Journal, 2000 , vol. 6, # 22 p. 4124 - 4131
反应条件
1: With boron tribromide in dichloromethane T=-12 - 0°C; 3 h; 2: With water in diethyl ether; dichloromethane T=20°C; 2 h; Further stages.;
参考文献
Gardinier, Kevin M.; Khoury, Richard G.; Lehn, Jean-Marie
Chemistry - A European Journal, 2000 , vol. 6, # 22 p. 4124 - 4131
反应条件
in ethanol
48 h; Heating;
参考文献
Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16748 - 16763
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
12 h; Heating;
参考文献
Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16748 - 16763
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
12 h; Heating;
参考文献
Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16748 - 16763
反应条件
1: 70 percent / Pd(PPh3)4 / toluene / 12 h / Heating
2: BBr3 / CH2Cl2 / 16 h / 25 °C
View Scheme
参考文献
Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16748 - 16763
反应条件
1: 61 percent / Pd(PPh3)4 / toluene / 12 h / Heating
2: BBr3 / CH2Cl2 / 16 h / 25 °C
View Scheme
参考文献
Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16748 - 16763
反应条件
1: 61 percent / Pd(PPh3)4 / toluene / 12 h / Heating
2: BBr3 / CH2Cl2 / 16 h / 25 °C
3: 45 mg / Dess-Martin reagent / CH2Cl2 / 6 h
View Scheme
参考文献
Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16748 - 16763
