2,5-二甲基-1-(2-吡啶基)吡咯合成路线 (共 4 条)
反应条件
scandium tris(trifluoromethanesulfonate) T=30°C; Paal-Knorr reaction; 0.5 h;
参考文献
Rahmatpour, Ali
Applied Organometallic Chemistry, 2011 , vol. 25, # 8 p. 585 - 590
反应条件
1: hex-3-yne-2,5-diol With ruthenium(II)-carbonyl-tris(triphenylphosphine) dihydride; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene 0.5 h; Inert atmosphereReflux; 2: 2-aminopyridine in toluene 23.5 h; Inert atmosphereReflux;
参考文献
Pridmore, Simon J.; Slatford, Paul A.; Taylor, James E.; Whittlesey, Michael K.; Williams, Jonathan M.J.
Tetrahedron, 2009 , vol. 65, # 44 p. 8981 - 8986
反应条件
9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene 24 h; Heating; Title compound not separated from byproducts.;
参考文献
Tetrahedron Letters, , vol. 48, # 29 p. 5115 - 5120
反应条件
trichlorophosphate T=0 - 60°C; Vilsmeier-Haack reaction; 3 h;
参考文献
Urbano, Mariangela; Guerrero, Miguel; Velaparthi, Subash; Crisp, Melissa; Chase, Peter; Hodder, Peter; Schaeffer, Marie-Therese; Brown, Steven; Rosen, Hugh; Roberts, Edward
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 22 p. 6739 - 6745