1-氯-2,2,6,6-四甲基哌啶合成路线 (共 4 条)
反应条件
chlorine; sodium hydroxide in water T=5 - 20°C; 1.5 h; Inert atmosphere; Reagent/catalystTime;
参考文献
BAYER INTELLECTUAL PROPERTY GMBH; FORD, Mark James
Patent: WO2013/120874 A1, 2013 ;
Location in patent: Page/Page column 8 ;
反应条件
sulfuryl dichloride in chloroform-d1 Inert atmosphere; Solvent;
参考文献
Saper, Noam I.; Snider, Barry B.
Journal of Organic Chemistry, 2014 , vol. 79, # 2 p. 809 - 813
反应条件
2,2'-azo-bisisobutyronitrile in trifluoroacetic acid T=80°C;
参考文献
Dneprovskii, A. S.; Mil'tsov, S. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 10 p. 1836 - 1840
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 10 p. 2037 - 2041
反应条件
in water Rate constant;
参考文献
Dannan; Crooks; Dittert; Hussain
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 7 p. 652 - 656