3-氨基吡嗪-2-甲酰胺合成路线 （共 24 条）
反应条件
ammonia in water T=20°C; 12 h;
参考文献
Duan, Chonggang; Jia, Jiong; Zhu, Rongxiu; Wang, Jianwu
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 4 p. 865 - 872
反应条件
hydroxylamine hydrochloride in methanol 0.666667 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 19, p. 1397 - 1402
反应条件
1: H2SO4 2: water; NH3 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 67, p. 1711
反应条件
sulfuric acid; dihydrogen peroxide; iron(II) sulfate T=0 - 15°C; 15 h;
参考文献
Vontor, Tomas; Palat, Karel; Lycka, Antonin
Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 5 p. 1306 - 1310
反应条件
1: 68 percent / 3.5 h / 105 °C 2: 80 percent / 0.58 h / Ambient temperature 3: 80 percent / aq. HCl / Ambient temperature 4: 5percent NaOH / H2O / 0.58 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 39, # 5 p. 823 - 829
反应条件
ammonia T=90°C; 3 h;
参考文献
Parish Jr.; Gilliom; Purcell; Browne; Spirk; White
Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 98 - 102
反应条件
1: 80 percent / 0.58 h / Ambient temperature 2: 80 percent / aq. HCl / Ambient temperature 3: 5percent NaOH / H2O / 0.58 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 39, # 5 p. 823 - 829
参考文献
Journal of the American Chemical Society, , vol. 80, p. 421,425
反应条件
in water 1 h; Heating; Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 39, # 5 p. 823 - 829
