2-乙酰氨基-5-氟甲苯合成路线 （共 14 条）
反应条件
1: acetic anhydride; nitric acid / 0 - 20 °C 2: hydrogenchloride / water / |Reflux View Scheme
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED; LAWSON, John David; SABAT, Mark; SMITH, Christopher; WANG, Haixia; CHEN, Young K.; KANOUNI, Toufike
Patent: WO2013/148603 A1, 2013 ;
反应条件
1: KMnO4, aq. MgSO4
2: aq. HCl
3: (i) NaNO2, aq. HCl, (ii) KI, aq. H2SO4
4: Cu, aq. KOH
5: LiAlH4
6: SOCl2
View Scheme
参考文献
Rajsner; Metysova; Svatek; et al.
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 3 p. 719 - 737
反应条件
1: KMnO4, aq. MgSO4
2: aq. HCl
3: (i) NaNO2, aq. HCl, (ii) KI, aq. H2SO4
4: Cu, aq. KOH
View Scheme
参考文献
Rajsner; Metysova; Svatek; et al.
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 3 p. 719 - 737
反应条件
1: KMnO4, aq. MgSO4
2: aq. HCl
3: (i) NaNO2, aq. HCl, (ii) KI, aq. H2SO4
4: Cu, aq. KOH
5: LiAlH4
View Scheme
参考文献
Rajsner; Metysova; Svatek; et al.
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 3 p. 719 - 737
