4,6-二羟基-3-苯并呋喃酮合成路线 (共 13 条)
反应条件
1: potassium carbonate / ethylene glycol dimethyl ether / 3 h / 80 °C 2: potassium hydroxide / methanol; water / Reflux 3: boron tribromide / dichloromethane / 0 - 20 °C View Scheme
参考文献
Haudecoeur, Romain; Ahmed-Belkacem, Abdelhakim; Yi, Wei; Fortune, Antoine; Brillet, Rozenn; Belle, Catherine; Nicolle, Edwige; Pallier, Coralie; Pawlotsky, Jean-Michel; Boumendjel, Ahcene
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5395 - 5402
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=80°C; 1 h;
参考文献
Nishida, Jun; Kawabata, Jun
Bioscience, Biotechnology and Biochemistry, 2006 , vol. 70, # 1 p. 193 - 202
反应条件
potassium carbonate in acetone
12 h; Heating;
参考文献
Kumaran, G.; Kulkarni, G. H.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 5 p. 436 - 437