4-羟基-1,3-二甲基-1H-喹啉-2-酮合成路线 （共 15 条）
反应条件
1: 1.) lithium diisopropylamide / 1.) THF, -70 deg C, 1 h; 2.) THF, 10 min. 2: 74 percent Turnov. / toluene / 0.75 h / Heating View Scheme
参考文献
Coppola, Gary M.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1217 - 1221
反应条件
1: 56 percent / 1.) C6H5MgBr / 1.) reflux, THF, 20 h; 2.) water, 4 degC; reaction of other anthranilonitriles 2: 30percent H2SO4 / 22 h / 120 °C View Scheme
参考文献
Bergman, Jan; Brynolf, Anna; Vuorinen, Eino
Tetrahedron, 1986 , vol. 42, # 13 p. 3689 - 3696
反应条件
in toluene 0.75 h; Heating;
参考文献
Coppola, Gary M.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1217 - 1221
反应条件
1) reflux, 3 h, 2) 100 deg C; Yield given. Multistep reaction;
参考文献
Chauncey; Grundon
Synthesis, 1990 , # 11 p. 1005 - 1007
反应条件
in benzene
45 h; Heating;
参考文献
Kumar, R. Nandha; Selvi, S. Thamarai; Suresh; Mohan
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 1 p. 187 - 188
