5-甲氧基喹唑啉-(2,4)二酮合成路线 （共 3 条）
反应条件
1: 1.8 g / POCl3; N,N-dimethylaniline / 16 h / Heating 2: 80 percent / aq. NaOH / tetrahydrofuran / 4 h / 20 °C View Scheme
参考文献
Ram, Vishnu Ji; Farhanullah; Tripathi, Brajendra K.; Srivastava, Arvind K.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 11 p. 2439 - 2444
反应条件
1.1: N,N-diethylaniline; trichlorophosphate / 6 h / Reflux 2.1: zinc; water; ammonia / dichloromethane / 2 h / Reflux 2.2: pH 7 View Scheme
参考文献
N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian; STOUT, Adam
Patent: WO2012/83165 A1, 2012 ;
反应条件
trichlorophosphate; N,N-dimethyl-aniline 5 h; Reflux;
参考文献
US2010/68197 A1, ;
Page/Page column 17 ;
