2-(4-氨基苯基)-n-甲基乙酰胺合成路线 (共 3 条)
反应条件
hydrogenchloride; 1,1'-carbonyldiimidazole; methylamine in tetrahydrofuran; ethanol; water; palladium
参考文献
Bristol-Myers Squibb Company
Patent: US5468768 A1, 1995 ;
US 5468768 A
反应条件
hydrogen; palladium on activated charcoal in ethanol P=2585.7 Torr; Yield given;
参考文献
Clark; Davenport
Journal of Pharmaceutical Sciences, 1987 , vol. 76, # 1 p. 18 - 20
反应条件
1: K2CO3 / H2O; tetrahydrofuran / 12 h / 50 °C 2: H2 / palladium on carbon / ethanol / 2585.7 Torr View Scheme
参考文献
Clark; Davenport
Journal of Pharmaceutical Sciences, 1987 , vol. 76, # 1 p. 18 - 20