1,5-二氟-2,4-二硝基苯合成路线 (共 24 条)
反应条件
sulfuric acid; nitric acid T=0 - 20°C; 1.5 h;
参考文献
Wu, Zehui; Hu, Ting; He, Lan; Gong, Bing
Organic Letters, 2012 , vol. 14, # 10 p. 2504 - 2507
反应条件
water; nitric acid; acetic anhydride in acetic acid T=50°C; 69 h;
参考文献
Journal of Fluorine Chemistry, , vol. 92, # 1 p. 27 - 32
反应条件
potassium fluoride T=200°C;
参考文献
US2891074 , ;
DE1018042 , ;
Chimija chim. Technol.Chem.Abstr., (NDVS) 1958 122 , p. 3110
反应条件
sulfuric acid; nitric acid
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 35, p. 142
Chem. Zentralbl., , vol. 84, # II p. 760
反应条件
ammonia in tetrahydrofuran T=20°C; 0.5 h;
参考文献
Yan, Yu; Liu, Zijie; Zhang, Jianjun; Xu, Ruiming; Hu, Xiao; Liu, Gang
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4189 - 4192
参考文献
Swarts
Recueil des Travaux Chimiques des Pays-Bas, 1916 , vol. 35, p. 142
Chem. Zentralbl., 1913 , vol. 84, # II p. 760
反应条件
1: 90 percent / Na2CO3 / acetonitrile / Ambient temperature 2: 69 percent / Na2CO3 / acetonitrile / Heating View Scheme
参考文献
Valli, Matthew J.; Tang, Yunzhao; Kosh, J. W.; Chapman, James M.; Sowell, J. Walter
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3141 - 3147
反应条件
1: 90 percent / Na2CO3 / acetonitrile / Ambient temperature 2: 41 percent / Na2CO3 / acetonitrile / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 17 p. 3141 - 3147
反应条件
1: 90 percent / Na2CO3 / acetonitrile / Ambient temperature 2: 29 percent / NH2NH2, Na2CO3 / acetonitrile / Heating View Scheme
参考文献
Valli, Matthew J.; Tang, Yunzhao; Kosh, J. W.; Chapman, James M.; Sowell, J. Walter
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3141 - 3147
反应条件
1: 90 percent / Na2CO3 / acetonitrile / Ambient temperature 2: 95 percent / ammonia, Na2CO3 / acetonitrile / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 17 p. 3141 - 3147