(3S,3aS,6S)-3-(叔丁基二甲基硅氧基)-6-(羟甲基)-3a,6-二甲基十氢-1H-环戊并[a]萘-7(2H)-酮合成路线 （共 4 条）
反应条件
1: With ozone in methanol; ethyl acetate T=-78°C; ozonolysis; 0.216667 h; 2: With dimethylsulfide T=20°C; Reduction; 2 h; 3: With potassium carbonate in acetone T=20°C; Hydrolysis;
参考文献
Kockert, Karlheinz; Vierhapper, Friedrich W
Tetrahedron, 2000 , vol. 56, # 51 p. 9967 - 9974
反应条件
1.1: 88 percent / imidazole / dimethylformamide / 12 h / 20 °C 2.1: O3 / ethyl acetate; methanol / 0.22 h / -78 °C 2.2: Me2S / 2 h / 20 °C 2.3: 87 percent / aq. K2CO3 / acetone / 20 °C View Scheme
参考文献
Kockert, Karlheinz; Vierhapper, Friedrich W
Tetrahedron, 2000 , vol. 56, # 51 p. 9967 - 9974
反应条件
1.1: 88 percent / imidazole / dimethylformamide / 12 h / 20 °C 2.1: O3 / ethyl acetate; methanol / 0.22 h / -78 °C 2.2: Me2S / 2 h / 20 °C 2.3: 87 percent / aq. K2CO3 / acetone / 20 °C View Scheme
参考文献
Kockert, Karlheinz; Vierhapper, Friedrich W
Tetrahedron, 2000 , vol. 56, # 51 p. 9967 - 9974
反应条件
1.1: 90 percent / NaBH4; aq. NaOH / CHCl3 / 5 h / 20 °C 2.1: 88 percent / imidazole / dimethylformamide / 12 h / 20 °C 3.1: O3 / ethyl acetate; methanol / 0.22 h / -78 °C 3.2: Me2S / 2 h / 20 °C 3.3: 87 percent / aq. K2CO3 / acetone / 20 °C View Scheme
参考文献
Kockert, Karlheinz; Vierhapper, Friedrich W
Tetrahedron, 2000 , vol. 56, # 51 p. 9967 - 9974
