3-氯-5-氰基苯甲酸甲酯合成路线 (共 3 条)
反应条件
thionyl chloride in N,N-dimethyl-formamide T=0 - 80°C; 1 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP2077262 A1, 2009 ;
Location in patent: Page/Page column 72 ;
反应条件
in dichloromethane; N,N-dimethyl-formamide
参考文献
Wagenen, Bradford Van; Stormann, Thomas M.; Moe, Scott T.; Sheehan, Susan M.; McLeod, Donald A.; Smith, Daryl L.; Isaac, Methvin Benjamin; Slassi, Abdelmalik
Patent: US2003/55085 A1, 2003 ;
US 20030055085 A1
反应条件
sodium hydroxide in methanol; ethyl acetate
参考文献
Wagenen, Bradford Van; Stormann, Thomas M.; Moe, Scott T.; Sheehan, Susan M.; McLeod, Donald A.; Smith, Daryl L.; Isaac, Methvin Benjamin; Slassi, Abdelmalik
Patent: US2003/55085 A1, 2003 ;
US 20030055085 A1