4-羟基-3-硝基苯甲腈合成路线 (共 24 条)
反应条件
ammonium nitrate; silica gel in chloroform; water 24 h; Reflux;
参考文献
Chehardoli, Gholamabbas; Zolfigol, Mohammad Ali; Azimi, Seyedeh Bahareh; Alizadeh, Ebadollah
Chinese Chemical Letters, 2011 , vol. 22, # 7 p. 827 - 830
反应条件
potassium phosphate; tri-tert-butyl phosphine; tris-(dibenzylideneacetone)dipalladium(0) in toluene T=50°C; 22 h;
参考文献
Chen, Guoshu; Chan, Albert S.C.; Kwong, Fuk Yee
Tetrahedron Letters, 2007 , vol. 48, # 3 p. 473 - 476
反应条件
sodium azide; trifluorormethanesulfonic acid in acetonitrile T=20°C; Schmidt reaction; 0.0333333 h;
参考文献
Rokade, Balaji V.; Prabhu, Kandikere Ramaiah
Journal of Organic Chemistry, 2012 , vol. 77, # 12 p. 5364 - 5370
反应条件
biphenyl; tetramethylammonium hydrogen difluoride in N,N-dimethyl acetamide T=80°C; 0.333333 h;
参考文献
Tetrahedron, , vol. 55, # 25 p. 7725 - 7738
反应条件
biphenyl; tetramethyl-ammonium fluoride in N,N-dimethyl acetamide T=80°C; 0.166667 h;
参考文献
Tetrahedron, , vol. 55, # 25 p. 7725 - 7738
反应条件
tetramethyl-ammonium fluoride in dimethyl sulfoxide T=100°C; Substitution; 1 h; Further byproducts given;
参考文献
Journal of Fluorine Chemistry, , vol. 94, # 1 p. 51 - 55
反应条件
acetamide; water; sodium acetate T=200°C;
参考文献
Chemische Berichte, , vol. 50, p. 1354
反应条件
sodium peroxynitrite in phosphate buffer T=20 - 25°C; Nitration; hydroxylation; pH=7.0; Kinetics; Further Variations:Solvents;
参考文献
Tetrahedron Letters, , vol. 40, # 38 p. 6933 - 6937
参考文献
Chemische Berichte, , vol. 30, p. 991
反应条件
1: nitric acid View Scheme
参考文献
Journal of the Chemical Society, , p. 642,645