1-(2-羟基乙基)-1,2,4-噻唑合成路线 （共 8 条）
反应条件
N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide in 1,4-dioxane T=70°C; 5 h;
参考文献
Burdeinyi; Popkov; Kharchevnikova
Russian Chemical Bulletin, 2009 , vol. 58, # 5 p. 936 - 939
参考文献
Merck Sharp and Dohme Ltd.
Patent: US6355798 B1, 2002 ;
US 6355798 B1
反应条件
in toluene T=80°C; 3.5 h;
参考文献
Burdeinyi; Popkov; Kharchevnikova
Russian Chemical Bulletin, 2009 , vol. 58, # 5 p. 936 - 939
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Journal of the American Chemical Society, , vol. 77, p. 621,623
参考文献
Angehrn, Peter; Hunziker, Daniel; Wyss, Pierre-Charles
Patent: US2003/199459 A1, 2003 ;
反应条件
potassium hydroxide; acetylene in 1,4-dioxane T=175 - 180°C; P=7600 - 9120 Torr; 1.5 h; Yield given. Yields of byproduct given;
参考文献
Gareev, G. A.; Kirillova, L. P.; Belousov, A. M.; Bukina, N. S.; Vereshchagin, L. I.
Journal of Organic Chemistry USSR (English Translation), 1980 , p. 1494 - 1498
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 8 p. 1751 - 1755
反应条件
potassium hydroxide in 1,4-dioxane T=175 - 180°C; P=7600 - 9120 Torr; 1.5 h; Yield given. Yields of byproduct given;
参考文献
Gareev, G. A.; Kirillova, L. P.; Belousov, A. M.; Bukina, N. S.; Vereshchagin, L. I.
Journal of Organic Chemistry USSR (English Translation), 1980 , p. 1494 - 1498
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 8 p. 1751 - 1755
反应条件
mercury(II) diacetate T=95 - 100°C; 2 h;
参考文献
Gareev, G. A.; Kirillova, L. P.; Belousov, A. M.; Bukina, N. S.; Vereshchagin, L. I.
Journal of Organic Chemistry USSR (English Translation), 1980 , p. 1494 - 1498
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 8 p. 1751 - 1755
