4,4'-二氨基-3,3'-二硝基二苯基醚合成路线 （共 17 条）
反应条件
1: 92 percent / K2CO3 / dimethylformamide / 10 h / 145 - 150 °C 2: 95 percent / NH2NH2; FeCl3; activated charcoal / dioxane 3: 93 percent / chlorobenzene / 2 h / 90 - 95 °C 4: 94 percent / HNO3; AcOH; Ac2O / urea / 50 - 60 °C 5: 96 percent / aq. NaOH / propan-2-ol / 80 °C View Scheme
参考文献
Russian Journal of General Chemistry, , vol. 75, # 10 p. 1509 - 1513
反应条件
1: KOH / dimethylformamide 2: hydrazine hydrate / Raney-nickel 3: 77.4 percent / acetic acid / 2 h / Ambient temperature 4: 82 percent / HNO3 / acetic acid / 2.5 h / 10 °C 5: 90 percent / 50percent HCl / 5 h / Heating View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 23, # 12 p. 1274 - 1278
反应条件
10 Pd/C; hydrogen in methanol T=20°C;
参考文献
Wang, Xiu-Jun; Yang, Ming-Li; Zhang, Lan-Ping; Yao, Tong; Chen, Cheng; Mao, Lian-Gang; Wang, Yin; Wu, Jie
Chinese Chemical Letters, 2014 , vol. 25, # 4 p. 589 - 592
反应条件
1: 1.) NaNO2, cc. H2SO4; 2.) EtOH, CuO / 1.) 1 h; 2.) AcOH, 1 h 2: 90 percent / SnCl2*2H2O / ethanol / 0.5 h / 70 °C View Scheme
参考文献
Bouanane,A. et al.
Bulletin de la Societe Chimique de France, 1974 , p. 641 - 648
反应条件
1: With water; sodium hydroxide
T=150°C; 1 h;
2: With sulfuric acid in water
Cooling;
参考文献
Imoto, Mitsutaka; Takeda, Motonori; Tamaki, Akihiro; Taniguchi, Hisaji; Mizuno, Kazuhiko
Organic Preparations and Procedures International, 2010 , vol. 42, # 2 p. 161 - 167
反应条件
tetra(n-butyl)ammonium hydroxide; water
T=100°C; Hofmann elimination; 1 h;
参考文献
Imoto, Mitsutaka; Takeda, Motonori; Tamaki, Akihiro; Taniguchi, Hisaji; Mizuno, Kazuhiko
Organic Preparations and Procedures International, 2010 , vol. 42, # 2 p. 161 - 167
反应条件
(i) NaNO2, H2SO4, (ii) Cu2O; Multistep reaction;
参考文献
Minato, Masaki; Lahti, Paul M.
Journal of Physical Organic Chemistry, 1994 , vol. 7, p. 495 - 502
