反应条件
1: 48 percent / CuI / tetrahydrofuran / 0.75 h / -78 °C 2: 1.) NaBH4 / 1.) ethanol, reflux, 15 min, 2.) ethanol, RT, 30 min 3: 1.) BF3*OEt2 / 1.) THF, 0 deg C, 5 min, 2.) THF, 0 deg C, 6 h 4: 83 percent / Ph3P, NaH / tetrahydrofuran / 0.5 h / Ambient temperature View Scheme
参考文献
Shibata, Koichi; Mitsunobu, Oyo
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 11 p. 3163 - 3173
