5-溴-2-氯嘧啶合成路线

参考文献

Nara, Susheel J.; Jha, Mukund; Brinkhorst, Johan; Zemanek, Tony J.; Pratt, Derek A.
Journal of Organic Chemistry, 2008 , vol. 73, # 23 p. 9326 - 9333

7664-41-7氨气+

32779-36-55-溴-2-氯嘧啶

7752-82-12-氨基-5-溴嘧啶

参考文献

Li, Yupeng; Shen, Mengjie; Zhang, Zhang; Luo, Jinfeng; Pan, Xiaofen; Lu, Xiaoyun; Long, Huoyou; Wen, Donghai; Zhang, Fengxiang; Leng, Fang; Li, Yingjun; Tu, Zhengchao; Ren, Xiaomei; Ding, Ke
Journal of Medicinal Chemistry, 2012 , vol. 55, # 22 p. 10033 - 10046

108-91-8环己胺+

32779-36-55-溴-2-氯嘧啶

886366-17-25-溴-2-环己基氨基嘧啶

参考文献

Li, Yupeng; Shen, Mengjie; Zhang, Zhang; Luo, Jinfeng; Pan, Xiaofen; Lu, Xiaoyun; Long, Huoyou; Wen, Donghai; Zhang, Fengxiang; Leng, Fang; Li, Yingjun; Tu, Zhengchao; Ren, Xiaomei; Ding, Ke
Journal of Medicinal Chemistry, 2012 , vol. 55, # 22 p. 10033 - 10046

32779-36-55-溴-2-氯嘧啶+

98-80-6苯硼酸

22536-62-52-氯-5-苯基嘧啶

参考文献

Colombo, Matteo; Giglio, Marco; Peretto, Ilaria
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 4 p. 1077 - 1081

3958-47-2+

32779-36-55-溴-2-氯嘧啶

22536-62-52-氯-5-苯基嘧啶

参考文献

Mosquera, Angeles; Riveiros, Ricardo; Sestelo, Jose Perez; Sarandeses, Luis A.
Organic Letters, 2008 , vol. 10, # 17 p. 3745 - 3748

960-16-7三丁基苯基锡+

32779-36-55-溴-2-氯嘧啶

22536-62-52-氯-5-苯基嘧啶

参考文献

Solberg, Jan; Undheim, Kjell
Acta Chemica Scandinavica, 1989 , vol. 43, # 1 p. 62 - 68

32779-36-55-溴-2-氯嘧啶+

1193-02-84-氨基苯硫酚

849035-61-6

参考文献

Khan, Saeed R.; Hallur, Gurulingappa; Hidalgo, Manuel; Jimeno, Antonio
Patent: US2009/99218 A1, 2009 ;
Location in patent: Page/Page column 20 ;

75-24-1三甲基铝+

32779-36-55-溴-2-氯嘧啶

22536-61-42-氯-5-甲基嘧啶

参考文献

Lu, Qingbo; Mangalagiu, Lonel; Benneche, Tore; Undheim, Kjell
Acta Chemica Scandinavica, 1997 , vol. 51, # 3 p. 302 - 306

505-66-8高哌嗪+

32779-36-55-溴-2-氯嘧啶

849021-44-91-(5-溴吡啶)[1,4]二氮杂庚烷

参考文献

GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT
Patent: WO2009/120789 A1, 2009 ;
Location in patent: Page/Page column 119 ;

32779-36-55-溴-2-氯嘧啶+

74497-02-2

886365-88-4

参考文献

ARRAY BIOPHARMA INC.; GENENTECH, INC.
Patent: WO2007/146824 A2, 2007 ;
Location in patent: Page/Page column 162 ;
WO 2007/146824 A2