5-溴-2-氯嘧啶合成路线

参考文献

Lee, Junwon; Kim, Jong Yup; Choi, Jungsub; Lee, Sung-Han; Kim, Jeongmin; Lee, Jinhwa
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 23 p. 7046 - 7049

67-56-1甲醇+

32779-36-55-溴-2-氯嘧啶

14001-66-25-溴-2-甲氧基嘧啶

参考文献

VIAMET PHARMACEUTICALS, INC.; HOEKSTRA, William, J.; RAFFERTY, Stephen, W.; YATES, Christopher, M.; SCHOTZINGER, Robert, J.; LOSO, Michael; SULLENBERGER, Michael
Patent: WO2012/177603 A2, 2012 ;
Location in patent: Page/Page column 74 ;

124-41-4甲醇钠+

32779-36-55-溴-2-氯嘧啶

14001-66-25-溴-2-甲氧基嘧啶

参考文献

Sun, Xicheng; Qiu, Jian; Strong, Sarah A.; Green, Louis S.; Wasley, Jan W.F.; Blonder, Joan P.; Colagiovanni, Dorothy B.; Mutka, Sarah C.; Stout, Adam M.; Richards, Jane P.; Rosenthal, Gary J.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5849 - 5853

4606-65-93-哌啶甲醇+

32779-36-55-溴-2-氯嘧啶

1189973-29-2

参考文献

RANBAXY LABORATORIES LIMITED
Patent: WO2009/156966 A1, 2009 ;
Location in patent: Page/Page column 34 ;
WO 2009/156966 A1

865-47-4叔丁醇钾+

32779-36-55-溴-2-氯嘧啶

121487-13-65-溴-2-(叔丁氧基)吡啶

参考文献

Arukwe, Joseph; Keilen, Gunnar; Undheim, Kjell
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1988 , vol. 42, # 8 p. 530 - 536

97-93-8三乙铝+

32779-36-55-溴-2-氯嘧啶

1722-12-92-氯嘧啶+

111196-81-72-氯-5-乙基嘧啶

参考文献

Acta Chemica Scandinavica, , vol. 51, # 3 p. 302 - 306

32779-36-55-溴-2-氯嘧啶+

411235-57-9环丙基硼酸

166740-44-92-氯-5-环丙基嘧啶

参考文献

ENVIVO PHARMACEUTICALS, INC.; RIPKA, Amy; SHAPIRO, Gideon; MCRINER, Andrew, J.; BURSAVICH, Matthew, Gregory
Patent: WO2013/142269 A1, 2013 ;
Location in patent: Paragraph 0648; 0649; 0650 ;

64-17-5乙醇+

32779-36-55-溴-2-氯嘧啶

17758-11-15-溴-2-乙氧基嘧啶

参考文献

Zhao, Yongfeng; Liao, Jiayu
Heterocycles, 2011 , vol. 83, # 5 p. 1145 - 1151

97-93-8三乙铝+

32779-36-55-溴-2-氯嘧啶

1722-12-92-氯嘧啶+

111196-81-72-氯-5-乙基嘧啶

参考文献

Acta Chemica Scandinavica, , vol. 51, # 3 p. 302 - 306

100-99-2三异丁基铝+