6-溴-1,2,3,4-四氢-2-喹啉酮合成路线 （共 21 条）
反应条件
Sodium bromate; hydrogen bromide; acetic acid T=20°C; Bromination; 0.333333 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 14 p. 1559 - 1562
反应条件
1: With sodium azide; methanesulfonic acid in dichloromethane T=0 - 20°C; 2: With sodium hydroxide in dichloromethane; water T=0°C;
参考文献
WO2012/162129 A1, ;
Page/Page column 35 ;
WO 2012/162129 A1
反应条件
sodium azide; sulfuric acid in benzene T=20 - 65°C; 0.333333 h;
参考文献
US2004/220206 A1, ;
Page 24; 32 ;
US 20040220206 A1
反应条件
titanium(III) chloride in tetrahydrofuran 1 h; Ambient temperature;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 67, # 9 p. 2542 - 1549
反应条件
1: dichloromethane / 2 h / 0 - 20 °C 2: AlCl3, aluminium chloride / 3 h / 120 °C 3: N-bromosuccinmide / N,N-dimethyl-formamide / 12 h / 0 - 20 °C View Scheme
参考文献
WO2012/148808 A1, ;
WO 2012/148808 A1
反应条件
1: AlCl3, aluminium chloride / 3 h / 120 °C 2: N-bromosuccinmide / N,N-dimethyl-formamide / 12 h / 0 - 20 °C View Scheme
参考文献
WO2012/148808 A1, ;
WO 2012/148808 A1
反应条件
1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; caesium carbonate / tetrahydrofuran; water / 16 h / |Reflux 2: tri-ruthenium(0)dodecacarbonyl / chlorobenzene; N,N-dimethyl acetamide / 20 - 120 °C / |Sealed tube View Scheme
参考文献
Journal of the American Chemical Society, , vol. 136, # 3 p. 1125 - 1131
反应条件
2: acetic acid; sodium acetate; bromine 3: aqueous HCl 4: sodium nitrite; water; hydrochloric acid / Behandeln der erhaltenen wss. Diazoniumsalz-Loesung mit Hypophosphorigsaeure (Phosphinsaeure) bei 0grad View Scheme
参考文献
Nippon Kagaku Zasshi, , vol. 75, p. 1035
Chem.Abstr., , p. 12470
反应条件
1: acetic acid; sodium acetate; bromine 2: aqueous HCl 3: sodium nitrite; water; hydrochloric acid / Behandeln der erhaltenen wss. Diazoniumsalz-Loesung mit Hypophosphorigsaeure (Phosphinsaeure) bei 0grad View Scheme
参考文献
Nippon Kagaku Zasshi, , vol. 75, p. 1035
Chem.Abstr., , p. 12470
反应条件
1: aqueous HCl 2: sodium nitrite; water; hydrochloric acid / Behandeln der erhaltenen wss. Diazoniumsalz-Loesung mit Hypophosphorigsaeure (Phosphinsaeure) bei 0grad View Scheme
参考文献
Nippon Kagaku Zasshi, , vol. 75, p. 1035
Chem.Abstr., , p. 12470
