D-亮氨酸合成路线

161832-74-2(R)-(+)-2-氨基-4-甲基-1,1-二苯基-1-戊醇

参考文献

Berkessel, Albrecht; Harnying, Wacharee; Duangdee, Nongnaphat; Neudoerfl, Joerg-M.; Groeger, Harald
Organic Process Research and Development, 2012 , vol. 16, # 1 p. 123 - 128

328-38-1D-亮氨酸

7533-40-6L-亮氨醇

参考文献

Wu, Shao-Yong; Hirashima, Akinori; Kuwano, Eiichi; Eto, Morifusa
Agricultural and Biological Chemistry, 1987 , vol. 51, # 2 p. 537 - 548

328-38-1D-亮氨酸

20312-37-2(R)-2-羟基-4-甲基戊酸

参考文献

Pettit, George R.; Hu, Shougang; Knight, John C.; Chapuis, Jean-Charles
Journal of Natural Products, 2009 , vol. 72, # 3 p. 372 - 379

328-38-1D-亮氨酸+

24424-99-5二碳酸二叔丁酯

16937-99-8Boc-D-亮氨酸

参考文献

Lassen, Kenneth M.; Lee, Jisun; Joullie, Madeleine M.
Journal of Organic Chemistry, 2010 , vol. 75, # 9 p. 3027 - 3036

328-38-1D-亮氨酸+

73371-96-7

16937-99-8Boc-D-亮氨酸

参考文献

Corbo, Filomena; Franchini, Carlo; Lentini, Giovanni; Muraglia, Marilena; Ghelardini, Carla; Matucci, Rosanna; Galeotti, Nicoletta; Vivoli, Elisa; Tortorella, Vincenzo
Journal of Medicinal Chemistry, 2007 , vol. 50, # 8 p. 1907 - 1915

1070-19-5N-重氮基氨基甲酸叔-丁基酯+

328-38-1D-亮氨酸

16937-99-8Boc-D-亮氨酸

参考文献

Kato; Izumiya
Bulletin of the Chemical Society of Japan, 1966 , vol. 39, # 10 p. 2242 - 2249

328-38-1D-亮氨酸+

41840-28-22-Boc-硫代-4,6-二甲基嘧啶

16937-99-8Boc-D-亮氨酸

参考文献

Murakami, Yukito; Nakano, Akio; Ikeda, Hidetsugu; Imori, Toru; Akiyoshi, Kazunari
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 1 p. 172 - 180

328-38-1D-亮氨酸

122999-39-7

参考文献

Theravance, Inc.
Patent: US8232306 B2, 2012 ;

328-38-1D-亮氨酸+

774-74-32-(2,6-二氯苯氧基)乙酰氯

80913-68-4

参考文献

Krewson,C.F.; Wood,J.W.
Journal of Organic Chemistry, 1960 , vol. 25, p. 143 - 145

328-38-1D-亮氨酸

80913-68-4

参考文献

Wood et al.
Patent: US2734816 , 1953 ;

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Krewson; Wood
Journal of Organic Chemistry, 1960 , vol. 25, p. 143,144