3-甲基-1H-吡咯-2-甲酸乙酯合成路线 （共 20 条）
反应条件
sodium ethanolate in ethanol T=20°C; 5 h;
参考文献
PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE BRIGHAM AND WOMEN'S HOSPITAL, INC.; TRUSTEES OF BOSTON UNIVERSITY
Patent: WO2009/23272 A1, 2009 ;
Location in patent: Page/Page column 36 ;
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran Heating / reflux;
参考文献
SEPRACOR INC.
Patent: US2005/143443 A1, 2005 ;
Location in patent: Page/Page column 39-41 ;
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=25°C; 18 h;
参考文献
WO2009/117421 A2, ;
Page/Page column 218 ;
WO 2009/117421 A2
参考文献
Chemische Berichte, , vol. 90, p. 79,81
Annali di Chimica (Rome, Italy), , vol. 46, p. 847,854
反应条件
1: concentrated H2SO4 / 40 °C View Scheme
参考文献
Chemische Berichte, , vol. 90, p. 79,81
反应条件
palladium on activated charcoal; charcoal MgO Hydrogenation;
参考文献
Journal of the American Chemical Society, , vol. 70, p. 1416,1420
参考文献
Journal of the American Chemical Society, , vol. 70, p. 1416,1420
反应条件
1: acetic acid; bromine / anschliessendes Behandeln mit SO2Cl2 und Erwaermen des erhaltenen Reaktionsgemisches mit H2O 2: ethanolic KOH 3: palladium/ magnesium oxide / coal catalyst; methanol / Hydrogenation 4: ethanolic NaOH 5: glycerol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 70, p. 1416,1420
反应条件
1: ethanolic NaOH 2: glycerol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 70, p. 1416,1420
反应条件
1: ethanolic KOH 2: palladium/ magnesium oxide / coal catalyst; methanol / Hydrogenation 3: ethanolic NaOH 4: glycerol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 70, p. 1416,1420
