1-甲基-4-苯基乙炔苯合成路线 （共 165 条）
反应条件
1: iodobenzene; acetylenecarboxylic acid With 1-methyl-pyrrolidin-2-one; 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); tetrabutyl ammonium fluoride T=20°C; Sonogashira coupling; 12 h; 2: para-bromotoluene T=90°C; 12 h;
参考文献
Moon, Jeongju; Jeong, Miso; Nam, Hyungoog; Ju, Jinhun; Moon, Joong Ho; Jung, Hyun Min; Lee, Sunwoo
Organic Letters, 2008 , vol. 10, # 5 p. 945 - 948
反应条件
potassium phosphate; copper(l) iodide; 8-hydroxy-quinoline in ethanol T=100°C; Suzuki Coupling; 12 h; Schlenk techniqueInert atmosphere;
参考文献
Liu, Jidan; Dai, Fenglin; Yang, Zhiyong; Wang, Sizhuo; Xie, Kai; Wang, Anwei; Chen, Xiang; Tan, Ze
Tetrahedron Letters, 2012 , vol. 53, # 42 p. 5678 - 5683
反应条件
silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium(0) in acetonitrile T=20°C; Hiyama Coupling; 12 h;
参考文献
Tang, Jiansheng; Guo, Cancheng
Journal of Chemical Research, 2014 , vol. 38, # 2 p. 123 - 127
反应条件
silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium(0) in acetonitrile T=20°C; Hiyama Coupling; 12 h;
参考文献
Tang, Jiansheng; Guo, Cancheng
Journal of Chemical Research, 2014 , vol. 38, # 2 p. 123 - 127
反应条件
silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium(0) in acetonitrile T=20°C; Hiyama Coupling; 12 h;
参考文献
Tang, Jiansheng; Guo, Cancheng
Journal of Chemical Research, 2014 , vol. 38, # 2 p. 123 - 127
反应条件
silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium(0) in acetonitrile T=20°C; Hiyama Coupling; 12 h;
参考文献
Tang, Jiansheng; Guo, Cancheng
Journal of Chemical Research, 2014 , vol. 38, # 2 p. 123 - 127
反应条件
1: lithium phenylacetylide With tri-isopropoxy-borane in ethylene glycol dimethyl ether T=-78°C; 1.5 h; 2: para-bromotoluene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; ethylene glycol dimethyl ether T=85°C; 2 h;
参考文献
Kosugi, Masanori; Tanji, Tadatoshi; Tanaka, Yukio; Yoshida, Atsushi; Fugami, Keigo; Kameyama, Masayuki; Migita, Toshihiko
Journal of Organometallic Chemistry, 1996 , vol. 508, # 1-2 p. 255 - 257
反应条件
C32H28BrFeIN3Pd; potassium acetate; silver(l) oxide in 1,2-dichloro-ethane T=80°C; 24 h;
参考文献
Li, Hong-Mei; Xu, Chen; Duan, Lu-Meng; Lou, Xin-Hua; Wang, Zhi-Qiang; Li, Zhen; Fan, Yao-Ting
Transition Metal Chemistry, 2013 , vol. 38, # 3 p. 313 - 318
反应条件
piperidine; tetrabutylammomium bromide in water T=60°C; Sonogashira coupling; 6 h;
参考文献
Jin, Myung-Jong; Lee, Dong-Hwan
Angewandte Chemie - International Edition, 2010 , vol. 49, # 6 p. 1119 - 1122
反应条件
piperidine; bis-triphenylphosphine-palladium(II) chloride in various solvent(s) T=20°C; Sonogashira reaction; 20 h;
参考文献
Ye, Chengfeng; Xiao, Ji-Chang; Twamley, Brendan; LaLonde, Aaron D.; Norton, M. Grant; Shreeve, JeaN'Ne M.
European Journal of Organic Chemistry, 2007 , # 30 p. 5095 - 5100
