2-甲基-1,3-二氧戊环-2-甲胺合成路线 （共 3 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate T=20°C; 5 h;
参考文献
Sako, Kumiko; Aoyama, Hiroshi; Sato, Shinichi; Hashimoto, Yuichi; Baba, Masanori
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3780 - 3790
反应条件
1: With toluene-4-sulfonic acid in toluene 15 h; Heating / reflux; 2: With hydrazine in ethanol T=65°C; 2.5 h;
参考文献
AVENTIS PHARMA DEUTSCHLAND GMBH
Patent: WO2004/69806 A2, 2004 ;
Location in patent: Page/Page column 27 ;
反应条件
sodium hydroxide in water 48 h; Reflux;
参考文献
Patenaude, Mathew; Campbell, Scott; Kinio, Dennis; Hoare, Todd
Biomacromolecules, 2014 , vol. 15, # 3 p. 781 - 790
