2,4-双(三氟甲基)苯甲酸合成路线 （共 4 条）
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran T=-75°C; 2 h;
参考文献
Schlosser, Manfred; Mongin; Porwisiak, Jacek; Dmowski, Wojciech; Bueker, Heinz H.; Nibbering, Nico M. M.
Chemistry - A European Journal, 1998 , vol. 4, # 7 p. 1281 - 1286
反应条件
n-butyllithium in diethyl ether; hexane; n-heptane
反应条件
N,N,N',N'',N''-pentamethyldiethylenetriamine; sec.-butyllithium in tetrahydrofuran T=-75°C; 2 h;
参考文献
Chemistry - A European Journal, , vol. 4, # 7 p. 1281 - 1286
反应条件
2,2,6,6-tetramethyl-piperidine; n-butyllithium 1.) THF, -78 deg C, 1.5 h, 2.) THF; Yield givenMultistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 55, # 4 p. 909 - 918
