1-金刚烷基-(2-氰基乙基)铵合成路线 （共 2 条）
反应条件
1-amino-adamantanehydrochloride 5 h; Heating;
参考文献
Plakhotnik, V. M.; Kovtun, V. Yu.; Leont'eva, N. A.; Petrova, I. G.; Pushkarskaya, N. L.; Galegov, G. A.
Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 7 p. 534 - 538
Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 7 p. 810 - 814
反应条件
1: 1-amino-adamantanehydrochloride With sodium hydrogencarbonate in water Saturated solution; 2: acrylonitrile in water Michael addition; Reflux;
参考文献
Joubert, Jacques; Dyk, Sandra Van; Green, Ivan R.; Malan, Sarel F.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 10 p. 5010 - 5020
