(R)-N-叔丁氧羰基-3-氨基-3-(4-羟基苯基)丙酸合成路线 （共 4 条）
反应条件
sodium carbonate in acetone T=0°C; 2 h;
参考文献
Cardillo, Giuliana; Gentilucci, Luca; Melchiorre, Paolo; Spampinato, Santi
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2755 - 2758
反应条件
1: 75 percent / Et3N / acetone; H2O / 2 h / 0 °C 2: penicillin G acylase/eupergit; aq. buffer / methanol / 20 °C / pH 7 3: 95 percent / aq. Na2CO3 / acetone / 2 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 24 p. 2755 - 2758
反应条件
1: AcONH4 / ethanol / 6 h / Heating 2: 75 percent / Et3N / acetone; H2O / 2 h / 0 °C 3: penicillin G acylase/eupergit; aq. buffer / methanol / 20 °C / pH 7 4: 95 percent / aq. Na2CO3 / acetone / 2 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 24 p. 2755 - 2758
反应条件
1: penicillin G acylase/eupergit; aq. buffer / methanol / 20 °C / pH 7 2: 95 percent / aq. Na2CO3 / acetone / 2 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 24 p. 2755 - 2758
