2,4,6,8-四氯嘧啶并[5,4-d]嘧啶合成路线 (共 13 条)
反应条件
1: acetone; NaI
2: dioxane; benzene
View Scheme
参考文献
Thomae G.m.b.H.
Patent: GB807826 , 1956 ;
反应条件
1: tetrahydrofuran / 0.33 h / 0 - 5 °C
2: 162 mg / dimethylsulfoxide / 6 h / 150 °C
View Scheme
参考文献
Basha, Anwer; Ratajczyk, James D.; Dyer, Richard D.; Young, Patrick; Carter, George W.; Brooks, Clint D.W.
Medicinal Chemistry Research, 1996 , vol. 6, # 1 p. 61 - 67
参考文献
Lin, Wenwei; Buolamwini, John K.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 16 p. 3906 - 3920