1.1: KOH / H2O; methanol / 48 h / 90 °C 1.2: tetrahydrofuran; H2O / 14 h / 20 °C / pH 10.5 2.1: H2 / Pd/C / methanol / 18 h / 20 °C / 1500.15 Torr 3.1: triethylamine / methanol / 5 - 20 °C View Scheme
参考文献
Lloyd, Richard C.; Lloyd, Michael C.; Smith, Mark E. B.; Holt, Karen E.; Swift, Jonathan P.; Keene, Philip A.; Taylor, Stephen J. C.; McCague, Raymond
Tetrahedron, 2004 , vol. 60, # 3 p. 717 - 728
1.1: KOH / H2O; methanol / 48 h / 90 °C 1.2: tetrahydrofuran; H2O / 14 h / 20 °C / pH 10.5 2.1: H2 / Pd/C / methanol / 18 h / 20 °C / 1500.15 Torr 3.1: triethylamine / methanol / 5 - 20 °C 4.1: triethylamine; DMAP / CH2Cl2 / 0.75 h / 0 °C 5.1: KOAc / dimethylformamide / 72 h / 60 °C 5.2: NaOMe / methanol / 7 h / 0 °C View Scheme
参考文献
Lloyd, Richard C.; Lloyd, Michael C.; Smith, Mark E. B.; Holt, Karen E.; Swift, Jonathan P.; Keene, Philip A.; Taylor, Stephen J. C.; McCague, Raymond
Tetrahedron, 2004 , vol. 60, # 3 p. 717 - 728
1.1: KOH / H2O; methanol / 48 h / 90 °C 1.2: tetrahydrofuran; H2O / 14 h / 20 °C / pH 10.5 2.1: triethylamine / methanol / 16 h / 0 - 20 °C 3.1: H2 / [(S,S)-(Me-DuPHOS)-Rh(COD)]BF4 / methanol / 14 h / 20 °C / 3750.38 Torr View Scheme
参考文献
Lloyd, Richard C.; Lloyd, Michael C.; Smith, Mark E. B.; Holt, Karen E.; Swift, Jonathan P.; Keene, Philip A.; Taylor, Stephen J. C.; McCague, Raymond
Tetrahedron, 2004 , vol. 60, # 3 p. 717 - 728
1.1: KOH / H2O; methanol / 48 h / 90 °C 1.2: tetrahydrofuran; H2O / 14 h / 20 °C / pH 10.5 2.1: triethylamine / methanol / 16 h / 0 - 20 °C 3.1: H2 / [(S,S)-(Me-DuPHOS)-Rh(COD)]BF4 / methanol / 14 h / 20 °C / 3750.38 Torr 4.1: triethylamine; DMAP / CH2Cl2 / 0.75 h / 0 °C 5.1: KOAc / dimethylformamide / 72 h / 60 °C 5.2: NaOMe / methanol / 7 h / 0 °C View Scheme
参考文献
Lloyd, Richard C.; Lloyd, Michael C.; Smith, Mark E. B.; Holt, Karen E.; Swift, Jonathan P.; Keene, Philip A.; Taylor, Stephen J. C.; McCague, Raymond
Tetrahedron, 2004 , vol. 60, # 3 p. 717 - 728
