4-氨基-呋喃[3,2-c]吡啶合成路线 （共 6 条）
反应条件
1: With N-(diphenylmethylene)amine; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene T=80°C; 3 h; Inert atmosphere; 2: With hydroxylamine in methanol T=20°C; 18 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; COOK II, James H.; MCDONALD, Ivar, M.; KING, Dalton; OLSON, Richard, E.; WANG, Nenghui; IWUAGWU, Christiana, I.; ZUSI, Christopher, F.; MACOR, John, E.
Patent: WO2011/53292 A1, 2011 ;
Location in patent: Page/Page column 135 ;
WO 2011/053292 A1
参考文献
Akzo Nobel N.V.
Patent: US6194409 B1, 2001 ;
反应条件
ammonium acetate T=155°C; Substitution; 72 h;
参考文献
Bourzat,J.-D.; Bisagni,E.
Bulletin de la Societe Chimique de France, 1971 , p. 1727 - 1730
参考文献
Bourzat,J.-D.; Bisagni,E.
Bulletin de la Societe Chimique de France, 1971 , p. 1727 - 1730
反应条件
1: Et3N 2: H2SO4 3: POCl3 4: N2H4*H2O 5: N2H4 / Raney-Ni View Scheme
参考文献
Bourzat,J.-D.; Bisagni,E.
Bulletin de la Societe Chimique de France, 1971 , p. 1727 - 1730
反应条件
1: H2SO4 2: POCl3 3: N2H4*H2O 4: N2H4 / Raney-Ni View Scheme
参考文献
Bourzat,J.-D.; Bisagni,E.
Bulletin de la Societe Chimique de France, 1971 , p. 1727 - 1730
