alpha-叔丁氧羰基-L-苯丙氨酰-L-亮氨酸合成路线 (共 14 条)
反应条件
1.1: 78 percent / NaOH / H2O / 3 h 2.1: isobutyl chloroformate; triethylamine / tetrahydrofuran / 0.02 h / 0 °C 2.2: 81 percent / triethylamine / tetrahydrofuran / 25 °C 3.1: 94 percent / lithium hydroxide monohydrate / methanol; H2O / 2 h / 25 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 12 p. 5006 - 5008
反应条件
1.1: 78 percent / NaOH / H2O / 3 h 2.1: isobutyl chloroformate; triethylamine / tetrahydrofuran / 0.02 h / 0 °C 2.2: 81 percent / triethylamine / tetrahydrofuran / 25 °C 3.1: 94 percent / lithium hydroxide monohydrate / methanol; H2O / 2 h / 25 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 12 p. 5006 - 5008
反应条件
1: 73 percent 2: 71 percent / aq. NaOH / dioxane View Scheme
参考文献
Recueil des Travaux Chimiques des Pays Bas, , vol. 101, # 12 p. 451 - 455
反应条件
ethylenediaminetetraacetic acid; phenyl-methyl-sulfonyl fluoride; water in aq. phosphate buffer T=30°C; Microbiological reactionEnzymatic reaction; Kinetics; Reagent/catalyst;
参考文献
Maurs, Michele; Acher, Francine; Azerad, Robert
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 22 - 26