1: With 4-(N,N-dimethlyamino)pyridine; chloro-trimethyl-silane; diisopropylamine in tetrahydrofuran T=20°C; 1 h; 2: With Schwartz's reagent in tetrahydrofuran T=0°C; 4 h; 3: benzoyl chloride With tert-butyl methyl ether; N,N-bis(2-hydroxyethyl)-glycine; sulfuric acid; sodium hydrogencarbonate more than 3 stages;
参考文献
NATURAL PHARMACEUTICALS INC.
Patent: WO2004/13096 A2, 2004 ;
Location in patent: Page 25 ;