反应条件
1: 1.) Et3N, Bu2BOTf / 1.) CH2Cl2, -70 to 20 deg C, 2 h, 2.) -78 to 0 deg C, 1 h 2: 81 percent / tetrahydrofuran / 0.25 h / -75 - 15 °C 3: 99 percent / NaN3, NH4Cl / ethanol / 8 h / 60 °C 4: 86 percent / H2 / 10percent Pd/C / ethyl acetate / 760 Torr 5: 76 percent / NaHCO3 / CH2Cl2 / 20 °C 6: 99 percent / pyridinium paratoluenesulfonate (PTSP) / toluene / 80 °C 7: 100 percent / LiOH, H2O / ethanol / 20 °C 8: 99 percent / DCC, DMAP / toluene / 2 h / 80 °C 9: 80 percent / HCOOH / 4 h / 20 °C 10: 87 percent / NaHCO3 / ethyl acetate; H2O 11: 89 percent / Zn, HOAc / methanol / 1 h / 60 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 33, # 36 p. 5185 - 5188
