sodium hydrogencarbonate in N,N-dimethyl-formamide T=23°C;

in methanol; diethyl ether; ethyl acetate

1: 2,6-dichloropyrazine With n-butyllithium in tetrahydrofuran T=-78 - -40°C; 0.416667 h; Inert atmosphere; 2: carbon dioxide in tetrahydrofuran T=-78 - 23°C; Inert atmosphere; 3: methyl iodide With sodium hydrogencarbonate in N,N-dimethyl-formamide 3 h; Inert atmosphere;