N-Boc-4-氨基苯硼酸频哪醇酯合成路线 （共 12 条）
反应条件
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,4-dioxane / 23 h / 80 °C / Inert atmosphere
2: triphenylphosphine / 1,2-dichloro-benzene / 12 h / 165 °C
3: hydrogenchloride / 1,4-dioxane; water / 1 h / 20 °C
4: acetic acid / 12 h / 20 °C
View Scheme
参考文献
Takeuchi, Tomoki; Oishi, Shinya; Watanabe, Toshiaki; Ohno, Hiroaki; Sawada, Jun-Ichi; Matsuno, Kenji; Asai, Akira; Asada, Naoya; Kitaura, Kazuo; Fujii, Nobutaka
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4839 - 4846
反应条件
1: cesium fluoride / tetrakis(triphenylphosphino)palladium / tetrahydrofuran / 50 h / Heating
2: 310 mg / TFA / CH2Cl2 / 6 h / 20 °C
View Scheme
参考文献
Schiek, Manuela; Al-Shamery, Katharina; Luetzen, Arne
Synthesis, 2007 , # 4 p. 613 - 621
