(3-氯-4-氟苯氧基)乙酸合成路线 （共 6 条）
反应条件
1: 3-chloro-4-fluorophenol With potassium hydroxide in dimethyl sulfoxide T=20°C; 0.166667 h; 2: bromoacetic acid methyl ester in dimethyl sulfoxide T=0 - 20°C; 3: With hydrogenchloride; water more than 3 stages;
参考文献
Martinborough, Esther; Fanning, Lev T.D.; Sheth, Urvi; Wilson, Dean; Termin, Andreas; Neubert, Timothy; Zimmermann, Nicole; Knoll, Tara; Whitney, Tara; Kawatkar, Arati; Lehsten, Danielle; Stamos, Dean; Zhou, Jinglan; Arumugam, Vijayalaksmi; Gutierrez, Corey
Patent: US2008/27067 A1, 2008 ;
Location in patent: Page/Page column 263 ;
反应条件
potassium hydroxide in water 1 h; Heating;
参考文献
RamaRao; Venkat Reddy; Maitraie; Ravikanth; Yadla; Narsaiah; Shanthan Rao
Tetrahedron, 2004 , vol. 60, # 52 p. 12231 - 12237
反应条件
1: sulfuric acid; aqueous sodium nitrite solution / Erhitzen des Reaktionsgemisches mit Kupfer(II)-sulfat und wss. Schwefelsaeure auf 180grad 2: aq. NaOH solution View Scheme
参考文献
Finger et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 94,95, 97
参考文献
Finger et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 94,95, 97
反应条件
1: 92 percent / potassium carbonate; sodium iodide / acetone / 3 h / Heating 2: 80 percent / potassium hydroxide / H2O / 1 h / Heating View Scheme
参考文献
RamaRao; Venkat Reddy; Maitraie; Ravikanth; Yadla; Narsaiah; Shanthan Rao
Tetrahedron, 2004 , vol. 60, # 52 p. 12231 - 12237
反应条件
thionyl chloride in hexane
Heating;
参考文献
RamaRao; Venkat Reddy; Maitraie; Ravikanth; Yadla; Narsaiah; Shanthan Rao
Tetrahedron, 2004 , vol. 60, # 52 p. 12231 - 12237
