N-(2-氧代丙基)草氨酸乙酯合成路线 （共 4 条）
反应条件
Dess-Martin periodane in dichloromethane T=0 - 20°C; 2 h;
参考文献
ELI LILLY AND COMPANY; HAMDOUCHI, Chafiq; LINESWALA, Jayana, Pankaj; MAITI, Pranab
Patent: WO2011/66183 A1, 2011 ;
Location in patent: Page/Page column 13 ;
WO 2011/066183 A1
参考文献
Good,R.H.; Jones,G.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 1938 - 1945
反应条件
1: With trichlorophosphate in toluene 16 h; Reflux; 2: With sodium hydrogencarbonate in water; toluene
参考文献
ELI LILLY AND COMPANY; HAMDOUCHI, Chafiq; LINESWALA, Jayana, Pankaj; MAITI, Pranab
Patent: WO2011/66183 A1, 2011 ;
Location in patent: Page/Page column 13 ;
WO 2011/066183 A1
反应条件
1: trichlorophosphate / toluene / 16 h / 20 °C / |Reflux
2: methanol; sodium tetrahydroborate / 0 - 20 °C
View Scheme
参考文献
NOVARTIS AG; BOCK, Mark Gary; LAGU, Bharat; PANDIT, Chetan; SASMAL, Sanjita; ULLRICH, Thomas
Patent: WO2013/128421 A1, 2013 ;
