1: 1,2,3-trimethoxyacridin-9(10H)-one With sodium hydride in tetrahydrofuran; mineral oil T=0°C; Inert atmosphere; 2: methyl iodide in tetrahydrofuran; mineral oil T=20°C; 2 h; Inert atmosphere;

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere 1.2: 2 h / 20 °C / Inert atmosphere 2.1: hydrogenchloride / ethanol; water / 12 h / Reflux View Scheme