N-苯基-1,3-噻唑-2-胺合成路线 （共 15 条）
反应条件
toluene-4-sulfonic acid in isopropyl alcohol T=80°C; 72 h;
参考文献
Schnuerch, Michael; Waldner, Birgit; Hilber, Karlheinz; Mihovilovic, Marko D.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 7 p. 2149 - 2154
反应条件
toluene-4-sulfonic acid in isopropyl alcohol T=80°C; 72 h;
参考文献
Schnuerch, Michael; Waldner, Birgit; Hilber, Karlheinz; Mihovilovic, Marko D.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 7 p. 2149 - 2154
反应条件
1: With potassium carbonate in acetonitrile 2: With toluene-4-sulfonic acid in acetonitrile T=50°C; 1 h;
参考文献
Schnuerch, Michael; Khan, Ather Farooq; Mihovilovic, Marko D.; Stanetty, Peter
European Journal of Organic Chemistry, 2009 , # 19 p. 3228 - 3236
反应条件
copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in 1,4-dioxane T=100°C; 22 h;
参考文献
Liu, Yifeng; Bai, Yajun; Zhang, Juan; Li, Yangyang; Jiao, Junping; Qi, Xiaoli
European Journal of Organic Chemistry, 2007 , # 36 p. 6084 - 6088
反应条件
copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in 1,4-dioxane T=100°C; 24 h;
参考文献
Liu, Yifeng; Bai, Yajun; Zhang, Juan; Li, Yangyang; Jiao, Junping; Qi, Xiaoli
European Journal of Organic Chemistry, 2007 , # 36 p. 6084 - 6088
反应条件
hydrogenchloride in water Hantzsch cyclization; 4 h; Reflux;
参考文献
Schnuerch, Michael; Khan, Ather Farooq; Mihovilovic, Marko D.; Stanetty, Peter
European Journal of Organic Chemistry, 2009 , # 19 p. 3228 - 3236
反应条件
copper diacetate in dichloromethane T=20°C; 4 h;
参考文献
Miloudi, Abdellah; El-Abed, Douniazad; Boyer, Gerard; Finet, Jean Pierre; Galy, Jean Pierre; Siri, Didier
European Journal of Organic Chemistry, 2004 , # 7 p. 1509 - 1516
反应条件
acetic acid T=100°C; 2 h;
参考文献
AVENTIS PHARMA DEUTSCHLAND GMBH
Patent: WO2004/22553 A1, 2004 ;
Location in patent: Page/Page column 26-27 ;
WO 2004/022553 A1
参考文献
Forlani,L. et al.
Synthesis, 1977 , p. 320 - 322
参考文献
Manzoni Ansidei; Travagli
Gazzetta Chimica Italiana, 1941 , vol. 71, p. 680,682
Full Text Show Details
Saijo
Yakugaku Zasshi, 1952 , vol. 72, p. 1014
Chem.Abstr., 1953 , p. 3298
