4-羟基-5,7-二甲氧基-3-喹啉甲腈合成路线 （共 5 条）
反应条件
in diphenylether 72 h; Heating;
参考文献
Boschelli; Wang; Ye; Wu; Zhang; Dutia; Powell; Wissner; Arndt; Weber
Journal of Medicinal Chemistry, 2001 , vol. 44, # 5 p. 822 - 833
反应条件
1: in tetrahydrofuran T=-78°C; 2: With acetic acid T=20°C;
参考文献
Zhang, Nan; Wu, Biqi; Powell, Dennis; Wissner, Allan; B. Floyd, Middleton; D. Kovacs, Eleonora; Toral-Barza, Lourdes; Kohler, Constance
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2825 - 2828
反应条件
1: 79 percent / 0.75 h / 120 °C 2: 88 percent / diphenyl ether; various solvent(s) / 72 h / Heating View Scheme
参考文献
Boschelli; Wang; Ye; Wu; Zhang; Dutia; Powell; Wissner; Arndt; Weber
Journal of Medicinal Chemistry, 2001 , vol. 44, # 5 p. 822 - 833
反应条件
1.1: Heating 2.1: tetrahydrofuran / -78 °C 2.2: AcOH / 20 °C View Scheme
参考文献
Zhang, Nan; Wu, Biqi; Powell, Dennis; Wissner, Allan; B. Floyd, Middleton; D. Kovacs, Eleonora; Toral-Barza, Lourdes; Kohler, Constance
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2825 - 2828
反应条件
N,N-dimethyl-formamide; trichlorophosphate T=110°C; 2 h;
参考文献
Boschelli; Wang; Ye; Wu; Zhang; Dutia; Powell; Wissner; Arndt; Weber
Journal of Medicinal Chemistry, 2001 , vol. 44, # 5 p. 822 - 833
