1.1: LiAlH4 / tetrahydrofuran / -10 - 20 °C 1.2: 73 percent / p-TsOH / CH2Cl2 / 20 °C 2.1: 69 percent / p-TsOH / CH2Cl2 / 17 h / 20 °C 3.1: 96 percent / oxalyl chloride; DMSO / CH2Cl2 / 1.4 h / -78 - -45 °C 4.1: rose bengal / benzene; methanol / 2 h / 20 °C / Irradiation View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '906717', constants.ctx, '0')">lithium diisopropyl amide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=-78&deg;C;&nbsp;<br /> &nbsp;