5-溴-2-羟基-3-甲基苯甲醛合成路线 （共 3 条）
反应条件
bromine in dichloromethane T=0°C; 1 h;
参考文献
Baleizao, Carlos; Gigante, Barbara; Garcia, Hermenegildo; Corma, Avelino
Journal of Catalysis, 2004 , vol. 221, # 1 p. 77 - 84
反应条件
1: formaldehyd With triethylamine; magnesium chloride in tetrahydrofuran T=20°C; 0.333333 h; 2: 2-hydroxy-5-bromotoluene in tetrahydrofuran 8 h; Reflux;
参考文献
Institute of Medicinal Molecular Design, Inc.
Patent: EP2272817 A1, 2011 ;
Location in patent: Page/Page column 271 ;
反应条件
1.1: boron tribromide / dichloromethane / 6 h / -78 - 0 °C 2.1: triethylamine; magnesium chloride / tetrahydrofuran / 0.33 h / 20 °C 2.2: 8 h / Reflux View Scheme
参考文献
Institute of Medicinal Molecular Design, Inc.
Patent: EP2272817 A1, 2011 ;
