2-(N-苯甲酰基)-氨基-5-氨基嘧啶合成路线 (共 3 条)
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; 20 h;
参考文献
CHROMA THERAPEUTICS LTD
Patent: WO2006/117552 A1, 2006 ;
Location in patent: Page/Page column 54-55 ;
WO 2006/117552 A1
反应条件
1: With triethylamine in dichloromethane 0.5 h; 2: With hydrogen; 1 Pd/C in methanol P=1551.49 Torr;
参考文献
MERCK SERONO S.A.; XIAO, Yufang; CHEN, Xiaoling; KARRA, Srinivasa R.; HUCK, Bayard R.; SUTTON, Amanda E.; GOUTOPOULOS, Andreas
Patent: WO2010/2779 A2, 2010 ;
Location in patent: Page/Page column 43 ;
WO 2010/002779 A2
反应条件
1: pyridine / 4 h / |Reflux; |Inert atmosphere 2: ethanol / 4 h / 20 °C View Scheme
参考文献
Tianjin Hemay Bio-Tech Co., Ltd.; ZHANG, Hesheng; CHEN, Yingwei; HE, Qingchao
Patent: EP2581372 A1, 2013 ;