4-甲氧基-α-甲基苯甲醇合成路线 （共 290 条）
反应条件
Lipase PS in di-isopropyl ether
T=30°C; Esterification; 56 h; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Kita, Yasuyuki; Takebe, Yasushi; Murata, Kenji; Naka, Tadaatsu; Akai, Shuji
Journal of Organic Chemistry, 2000 , vol. 65, # 1 p. 83 - 88
反应条件
1: 4-methoxy-α-methylbenzyl alcohol With (S,R(P))-2-phenyl-2,3-dihydroimidazo[1,2-a]pyrindinyl-pentaphenylcyclopentadienyliron; N-ethyl-N,N-diisopropylamine in toluene
T=0°C; 0.0833333 h;
2: propionic acid anhydride in toluene
T=0°C; 8 h; optical yield given as percent eeenantioselective reaction;
参考文献
Belmessieri, Dorine; Joannesse, Caroline; Woods, Philip A.; MacGregor, Callum; Jones, Caroline; Campbell, Craig D.; Johnston, Craig P.; Duguet, Nicolas; Concellon, Carmen; Bragg, Ryan A.; Smith, Andrew D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 2 p. 559 - 570
反应条件
lipase Amano PS enzyme in di-isopropyl ether
T=30°C; 56 h; Yield given. Yields of byproduct given;
参考文献
Kita, Yasuyuki; Takebe, Yasushi; Murata, Kenji; Naka, Tadaatsu; Akai, Shuji
Tetrahedron Letters, 1996 , vol. 37, # 41 p. 7369 - 7372
反应条件
in water
24 h; Geotrichum candidum IFO 5767, without and with allyl alcohol as an additive; Product distribution;
参考文献
Bouzemi, Nassima; Debbeche, Hanane; Aribi-Zouioueche, Louisa; Fiaud, Jean-Claude
Tetrahedron Letters, 2004 , vol. 45, # 3 p. 627 - 630
反应条件
(R)-(+)-N-methylbenzoguanidine; trimethylacetic anhydride in diethyl ether
T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Nakata, Kenya; Shiina, Isamu
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 7092 - 7096
反应条件
Pseudomonas cepacia lipase in di-isopropyl ether
T=30°C; Esterification; Racemate separation; 21 h; Title compound not separated from byproducts;
参考文献
Athawale, Vilas; Manjrekar, Narendra
Synlett, 2000 , # 2 p. 225 - 226
反应条件
tertiary amine-based nucleophilic catalyst in 1,1-dimethylpropan-1-ol
T=0°C; 15 h;
参考文献
Jeong, Kyu-Sung; Kim, Soong-Hyun; Park, Hyun-Jin; Chang, Kyoung-Jin; Kwan, Soo Kim
Chemistry Letters, 2002 , # 11 p. 1114 - 1115
反应条件
(S)-(4-tert-butyl-2-thioxothiazolidin-3-yl)[4-(dimethylamino)pyridin-3-yl]methanone; triethylamine
T=20°C; 12 h;
参考文献
Yamada, Shinji; Misono, Tomoko; Iwai, Yuko; Masumizu, Ayako; Akiyama, Yukiko
Journal of Organic Chemistry, 2006 , vol. 71, # 18 p. 6872 - 6880
反应条件
3 A molecular sieve; Humicola insolens ferulic acid esterase
T=45°C; 72 h;
参考文献
Machado, Luciana L.; Lemos, Telma L.G.; de Mattos, Marcos Carlos; de Oliveira, Maria da Conceicao F.; de Gonzalo, Gonzalo; Gotor-Fernandez, Vicente; Gotor, Vicente
Tetrahedron Asymmetry, 2008 , vol. 19, # 12 p. 1418 - 1423
反应条件
2-acetyloxy-1-propene; lipase YS in di-isopropyl ether
T=30°C; 29 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Naemura, Koichiro; Fukuda, Ritsuko; Konishi, Masayoshi; Hirose, Keiji; Tobe, Yoshito
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 10 p. 1253 - 1256
