4-甲氧基-α-甲基苯甲醇合成路线 （共 290 条）
反应条件
iodine in nitromethane
T=80°C; 1 h;
参考文献
Thirupathi, Ponnaboina; Kim, Sung Soo
Tetrahedron, 2010 , vol. 66, # 16 p. 2995 - 3003
反应条件
1: 89 percent / La(OTf)3 / nitromethane / 3.5 h / 20 °C
2: 87 percent / Yb(OTf)3 / nitromethane / 23 h / 50 °C
View Scheme
参考文献
Noji, Masahiro; Konno, Yosuke; Ishii, Keitaro
Journal of Organic Chemistry, 2007 , vol. 72, # 14 p. 5161 - 5167
反应条件
sodium hydrogen sulphate; silica gel in 1,2-dichloro-ethane
T=60°C; 4 h;
参考文献
Aoyama, Tadashi; Koda, Shuichi; Takeyoshi, Yuka; Ito, Tetsuhiro; Takido, Toshio; Kodomari, Mitsuo
Chemical Communications, 2013 , vol. 49, # 59 p. 6605 - 6607
反应条件
potassium hydroxide in dimethyl sulfoxide
0.5 h; Ambient temperature;
参考文献
Mohan, Raju; Katzenellenbogen, John A.
Journal of Organic Chemistry, 1984 , vol. 49, # 7 p. 1238 - 1246
反应条件
tert.-butylhydroperoxide; Rh+(diphos) in methanol
T=70°C;
参考文献
Mueller, Paul; Idmoumaz, Hamid
Journal of Organometallic Chemistry, 1988 , vol. 345, p. 187 - 200
反应条件
sodium hydrogensulfite
T=60°C; 14 h;
参考文献
Yu, Jun-Lai; Wang, Hui; Zou, Kai-Feng; Zhang, Jia-Rui; Gao, Xiang; Zhang, Dan-Wei; Li, Zhan-Ting
Tetrahedron, 2013 , vol. 69, # 1 p. 310 - 315
反应条件
1: sodium hydride / diethyl ether / 12 h / 0 °C
2: methanol; acetonitrile / 25 °C / var. concentration of MeCN in MeCN-MeOH mixture
View Scheme
参考文献
Lee, Ikchoon; Kim, Hyung Yoon; Kang, Han Keun; Lee, Hai Whang
Journal of Organic Chemistry, 1988 , vol. 53, # 12 p. 2678 - 2683
反应条件
tert.-butylhydroperoxide; Rh+(diphos)
T=70°C;
参考文献
Mueller, Paul; Idmoumaz, Hamid
Journal of Organometallic Chemistry, 1988 , vol. 345, p. 187 - 200
反应条件
perchloric acid; sodium perchlorate in water
T=22°C; Product distribution;
参考文献
Richard, John P.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1373 - 1383
反应条件
n-butyllithium
1.) tetrahydrofurane, hexane, 5 deg C, 15 min, then DMSO, 25 deg C, 15 min; 2.) 25-28 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Okamoto, Kunio; Takeuchi, Ken'ichi; Inoue,Takeshi
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 842 - 848
