(2S)-N-甲基-2-吡咯烷甲酰胺盐酸盐合成路线 （共 5 条）
反应条件
hydrogenchloride in methanol T=20°C; 1 h;
参考文献
Shendage, Deepak M.; Froehlich, Roland; Haufe, Guenter
Organic Letters, 2004 , vol. 6, # 21 p. 3675 - 3678
反应条件
1: 99 percent / N-methylmorpholine; isobutyl chloroformate / tetrahydrofuran; H2O / 1 h / -20 °C 2: 98 percent / HCl / methanol / 1 h / 20 °C View Scheme
参考文献
Shendage, Deepak M.; Froehlich, Roland; Haufe, Guenter
Organic Letters, 2004 , vol. 6, # 21 p. 3675 - 3678
反应条件
potassium carbonate in ethanol
参考文献
Nifontov, V. I.; Bel'skaya, N. P.; Chernov, V. A.; Galyamova, I. V.; Khvorova, N. M.; et al.
Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 8 p. 577 - 581
Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 8 p. 901 - 905
反应条件
1: 41 percent / CHCl3 / Ambient temperature 2: HCl / dioxane View Scheme
参考文献
Yonezawa; Jingu; Katakai
Synthetic Communications, 1994 , vol. 24, # 9 p. 1239 - 1246
参考文献
Nilsson, Mikael; Haemaelaeinen, Markku; Ivarsson, Maria; Gottfries, Johan; Xue, Yafeng; Hansson, Sebastian; Isaksson, Roland; Fex, Tomas
Journal of Medicinal Chemistry, 2009 , vol. 52, # 9 p. 2708 - 2715
