2'-羟基-2-(4-甲氧基亚苄基)乙酰苯合成路线 (共 22 条)
反应条件
1: o-hydroxyacetophenone With sodium hydride in tetrahydrofuran; mineral oil T=20°C; Aldol condensation; Inert atmosphere; 2: 4-methoxy-benzaldehyde in tetrahydrofuran; mineral oil T=20°C; Aldol condensation; Inert atmosphere;
参考文献
Sagrera, Gabriel; Bertucci, Ana; Vazquez, Alvaro; Seoane, Gustavo
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3060 - 3073
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 28, p. 279 - 281
反应条件
potassium hydroxide in ethanol T=20°C; Claisen-Schmidt Condensation; 24 h;
参考文献
KAOHSIUNG MEDICAL UNIVERSITY; WU, YANG-CHANG; CHANG, FANG-RONG; HSIEH, TUSTY-JIUAN; JUO, SUH-HANG; LIN, AN-SHEN; DU, YING-CHI
Patent: US2013/40996 A1, 2013 ;
Location in patent: Paragraph 0037-0040 ;
反应条件
T=150°C; 0.0833333 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1299 - 1305
反应条件
ethanol in dichloromethane Kinetics;
参考文献
Chemistry - A European Journal, , vol. 18, # 40 p. 12764 - 12772
反应条件
iodine in dimethyl sulfoxide 1 h; Reflux;
参考文献
Sagrera, Gabriel; Seoane, Gustavo
Synthesis, 2010 , # 16 art. no. M06509SS, p. 2776 - 2786
反应条件
iodine; acetic acid in ethanol; water Reflux;
参考文献
Sagrera, Gabriel; Bertucci, Ana; Vazquez, Alvaro; Seoane, Gustavo
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3060 - 3073
反应条件
silica ferric hydrogensulphate in ethanol Michael Addition; 9 h; Reflux;
参考文献
Eshghi, Hossein; Rahimizadeh, Mohammad; Mousavi, Seyed Mohsen
Natural Product Research, 2014 , vol. 28, # 7 p. 438 - 443
反应条件
iodine; acetic acid in ethanol; water Reflux;
参考文献
Sagrera, Gabriel; Bertucci, Ana; Vazquez, Alvaro; Seoane, Gustavo
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3060 - 3073
参考文献
Dhoubhadel, S. P.; Tuladhar, Sudersan M.; Tuladhar, Sarbajna M.; Wagley, Pradyumna P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 6 p. 511 - 512