5-(4-溴苯基)异噁唑-3-羧酸合成路线 （共 3 条）
反应条件
1: With sodium hydroxide in ethanol T=20°C; 24 h; 2: With hydrogenchloride in water pH=2;
参考文献
Andrzejak, Virginie; Muccioli, Giulio G.; Body-Malapel, Mathilde; El Bakali, Jamal; Djouina, Madjid; Renault, Nicolas; Chavatte, Philippe; Desreumaux, Pierre; Lambert, Didier M.; Millet, Regis
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 12 p. 3777 - 3786
反应条件
1.1: hydroxylamine hydrochloride / ethanol / 2 h / Reflux 2.1: sodium hydroxide / ethanol / 24 h / 20 °C 2.2: pH 2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 12 p. 3777 - 3786
反应条件
1.1: sodium ethanolate / ethanol / 2 h / Reflux 1.2: 1 h 2.1: hydroxylamine hydrochloride / ethanol / 2 h / Reflux 3.1: sodium hydroxide / ethanol / 24 h / 20 °C 3.2: pH 2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 12 p. 3777 - 3786
