1-(3-(二甲基氨基)苯基)-2,2,2-三氟乙酮合成路线 （共 3 条）
反应条件
1: 48 percent / KOH / H2O / 2.33 h 2: 1.) t-BuLi / 1.) THF, hexane, from -78 deg C to -70 deg C, 30 min, 2.) Et2O, THF, hexane, -78 deg C, 10 min View Scheme
参考文献
Nair, Haridasan K.; Lee, Keun; Quinn, Daniel M.
Journal of the American Chemical Society, 1993 , vol. 115, # 22 p. 9939 - 9941
反应条件
tert.-butyl lithium 1.) THF, hexane, from -78 deg C to -70 deg C, 30 min, 2.) Et2O, THF, hexane, -78 deg C, 10 min; Multistep reaction;
参考文献
Nair, Haridasan K.; Lee, Keun; Quinn, Daniel M.
Journal of the American Chemical Society, 1993 , vol. 115, # 22 p. 9939 - 9941
参考文献
Salvador,R.L.; Saucier,M.
Tetrahedron, 1971 , vol. 27, p. 1221 - 1226
